ChemSource Solutions offers a variety of services that are enabling clients to optimize both their internal resources as well as their returns on external collaborations. We customize strategies to navigate the transition between discovery and development, and support outsourcing activities both tactically and operationally.
- Enable Transition Between Late Discovery and Early Development: Transitioning a medicinal chemistry program from late discovery into early development can be complex, expensive and encumbered by timeline delay. CSS leverages its extensive experience and network of premiere service providers to:
- Develop client-specific strategies that provide the right balance between Asian and North American CRO and service providers.
- Connect clients with the best-fit service partner (CRO, CMO, solid state characterization, labeled compounds synthesis, high throughput experimentation, etc.)
- Manage the selection process that will result in the identification of the appropriate CRO to support the preparation of the IND enabling batches.
- Provide scientific oversight and guidance over the chemical development activities executed by our client’s CRO.
- Professional Reagent Sourcing Services: Through strong partnership with a professional sourcing service, CSS offers rapid assessment of cost and availability of reagents. The additional benefits include:
- Speed and flexibility – Timely identification and ordering of materials through a flexible, extensive global network of suppliers.
- Vendor management – All vendors are verified and rated based on delivery timing, quality, service and ability to provide documentation.
- Cost savings – CSS and his sourcing partner benefit from high volume discount. We willnegotiate with vendors to pass savings on directly to our clients.
- Accessibility – A dedicated team of Sourcing Specialists and Order Managers are available online, by email and by phone for questions, support and additional requests.
- Expert Guidance on Optimal Outsourcing Strategies: Assigning internal resources to support the sourcing of scale-up activities can be time-consuming and burdensome. ChemSource Solutions relieves the strain anddrives client productivity with the following services:
- Provide advise on the best outsourcing option
- Connecting clients with CSS network of preferred partners (Asia and North America)
- Preparation of Outsourcing Package – Request for Proposal
- Submission of Proposal and Quote Evaluation
- Track Progress and Weekly Assessment Updates
- Tracking of CRO’s Key Performance Indicator
- Management of Synthetic FTE to Support Medicinal Chemistry Efforts: CSS is able to support the progression of Medicinal Chemistry Programs by managing a group of Synthetic FTE with additional offerings to:
- Define new synthetic routes that will allow access to novel intermediates
- Improve known synthetic sequence to access compounds of interest (enabling SAR)
- Support the route optimization and initial scale-up of potential development candidates. These scale-up activities are critical to support the transition between late discovery and early development.